Scientific Name: Mesocricetus auratus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Cricetidae
Summary: The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_0014 | 2021.04 | 10X Genomics | Frontal | Normal | 3269 | Link |
| Vthunter_0015 | 2021.04 | 10X Genomics | Heart | Normal | 3063 | Link |
| Vthunter_0016 | 2021.04 | 10X Genomics | Kidney | Normal | 7180 | Link |
| Vthunter_0017 | 2021.04 | 10X Genomics | Liver | Normal | 18383 | Link |
| Vthunter_0018 | 2021.04 | 10X Genomics | Lung | Normal | 1695 | Link |
| Vthunter_110072 | 2019.12 | MARS-seq | TotalBrain | Normal | 768 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in fat (RPKM 198.4), placenta (RPKM 170.8) and 25 other tissues
